DL-01/2010-11

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Project No. : DL-01/2010-11

Year. : 2010-11

Project Title: Spectroscopic Analysis of medicinal plants from an Ayurvedic perspective to aid in new standardization and Quality assessment parameters

State: Delhi

Theme: Pharmacognosy/ Phyto-chemistry

Plant species: Abutilon indicum , Acacia nilotica , Aconitum ferox , Agaricus campestris , Alpinia galangal , Alpinia officinarum , Andrographis paniculata , Annona squamosal , Asparagus racemosus , Bauhinia purpurea , Benincasa cerifera , Borassus flabellifer , Brassica campestris , Brassica juncea , Capsicum annuum , Carum carvi , Cassia fistula , Cassia tora , Centella asiatica , Cinnamomum tamala , Cissampelos pareira , Citrus medica , Coccinia grandis , Croton tiglium , Cucumis sativus , Cuminum cyminum , Dolichos biflorus , Euphorbia neriifolia , Ferula narthex , Ficus benghalensis , Ficus lacor , Ficus racemosa , Ficus religiosa , Garcinia indica , Glycyrrhiza glabra , Gossypium herbaceum , Indigofera tinctoria , Leptadenia reticulate , Mangifera indica , Mentha piperita , Momordica charantia , Morus alba , Musa paradisiaca , Nyctanthes arbor-tristis , Ougeinia dalbergioides , dalbergioides , Phaseolus aureus , Phoenix sylvestris , Picrorhiza kurroa , Piper chaba , Piper longum , Piper nigrum , Plantago ovata , Plumbago zeylanica , Prunus amygdalus , Pueraria tuberosa , Raphanus sativus , Rauvolfia serpentina , Salmalia malabarica , Sida cordifolia , Solanum nigrum , Swertia chirayta , Symplocos racemosa , Tamarindus indica , Terminalia arjuna , Terminalia bellerica , Thespesia populnea , Tribulus terrestris , Trigonella foenum-graecum , Vitis vinifera , Woodfordia cordifolia , Zingiber officinale

Principal Investigator & Organization : Dr. Rama Jayasundar, Department of NMR, All India Institute of Medical Science, Ansari Nagar, New Delhi - 110029.

Status: Closed

Summary of Project / Major Outcome /Achievements : For standardization and quality assessment parameters of medicinal plants in Ayurveda, spectroscopic metabolomics have been used for few medicinal plants from three different taste categories viz., sweet, pungent and multiple taste- Tribulus terrestris, Vitis vinifera and Glycyrrhiza glabrafrom; sweet category; Piper longum, Cuminum cyminum, Capsicum annum from pungent group; Emblica officinalis with five tastes. While Electronic tongue was used for evaluation of the sensorial property of taste, the chemical properties were studied with Nuclear Magnetic Resonance (NMR), Fourier Transform Infra-Red (FTIR) and Laser Induced Breakdown Spectroscopy (LIBS). In terms of taste and phytochemical profiles all samples were unique but with similarities within each group. While the sensor response in E-tongue showed similarities within the sweet and pungent categories, NMR spectra in the aromatic region showed close similarities between the plants in the sweet category. The sensory, phytochemical and phytoelemental profiles of E. officinalis (with five rasa) in particular, were unique. In conclusion, combined sensorial and chemical descriptors is a promising approach for a comprehensive evaluation and fingerprinting of the Ayurvedic pharmacological parameterrasa.

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